MuscleMeds Methyl ARIMATEST 120 caps + 60 Fastsorb Tabs

Dual Action Pharmadynamic Testosterone Technology Increases Testosterone Over 10,000 pg/mL**

* 7-Arimatase: Anti-Aromatase and Testosterone Elevating
* Dihydrotase: DHT Blocking and Testosterone Elevating
* SubZorb Delivery - Bio-Potency Amplification
* Clinically Tested**

Methyl ARIMATEST represents one of the greatest research-based sports science breakthroughs in testosterone optimization, featuring dual anti-aromatase and 5 Alpha- reductase inhibition. The ingredients in this powerful formula have been shown to increase testosterone to over 10,000 pg/mL.

Compelling new research reveals a more effective way to increase testosterone levels based on a triad of intricate factors: multi-pathway physiological testosterone optimization; methylation techniques for enhanced bio-effectiveness and the application of an advanced bioactive deliver system technology.

The Science Behind Methyl Arimatest

In the development of Methyl ARIMATEST, the MuscleMeds research team knew it was paramount to inhibit the conversion of testosterone into DHT and estrogen if they were going to achieve the desired elevated and sustained levels of testosterone for maximum anabolic effects. To achieve this, MuscleMeds researchers focused on how to optimize the endogenous production of testosterone, while inhibiting negative feedback inhibition. To understand the importance of this, you must understand that the human body is a complex system of checks and balances. The production of testosterone is controlled at the hypothalamus-pituitary-testes axis. At this axis, the levels of testosterone are governed by a variety of complex signals and surges, and a negative feedback mechanism exist. This negative feedback is a physiological turn off switch, which shuts down testosterone production in response to trying to maintain homeostasis. Methyl ARIMATEST is scientifically formulated to override this negative feedback off switch to sustain testosterone production and promote the higher levels of testosterone needed to trigger anabolically activated� muscle growth.

Key Mechanisms of Action and Compounds in Methyl ARIMATEST
DHT (Dihydrotestosterone) and 5 Alpha-reductase Inhibition

In the body, some testosterone gets converted to DHT, which primarily exerts what is termed androgenic effects, such as body and facial hair growth, acne and prostate growth. Increasing testosterone levels can therefore lead to increasing DHT levels and androgenic effects, versus the more desirable anabolic muscle-building effects that testosterone exerts in muscle tissue. Research has shown that blocking the 5 Alpha-reductase enzyme will inhibit the conversion of testosterone to DHT. Additionally, researchers have recently hypothesized that reducing testosterone's conversion to DHT will allow more testosterone to remain in the bloodstream thereby increasing testosterone levels. To accomplish the goal of reducing the conversion of testesterone to DHT, Methyl ARIMATEST utilizes a clinically tested 5 Alpha-reductase inhibitor, Dihydrotase.

Dihydrotase Clinically tested 5 Alpha-reductase Inhibitor
Testosterone Boosting Study Results

The Dihydrotase complex used in Methyl ARIMATEST was tested in an independent clinical research study, which reported significant elevations in testosterone levels and decreased levels of dihydrotesosterone (DHT). Healthy males were recruited for this 14-day study to determine the 5 Alpha-reductase inhibitor effects of the ingredients in the Dihydrotase complex. By the end of the 14-day study period, testosterone levels increased by an astounding average of 10,066 pg/mL. A significant lowering of DHT was also reported to be experienced by the research subjects.

Aromatase Inhibitors: Lower Estrogen and Boost Testosterone

Another mode of action in testosterone optimization is the use of aromatase inhibitors. Circulating estrogens in the body can be decreased by inhibition of their biosynthesis from testosterone. The metabolic target of estrogen synthesis inhibition is aromatase enzymes. Aromatase enzymes are part of the body's biochemistry system that are used in the conversion of testosterone to estrogen. So, when aromatase enzyme activity is inhibited (blocked), this prevents conversion of testosterone into estrogen. For this central role in the production of estrogen, aromatase has become a central enzyme target of inhibition for people who want to optimize their testosterone levels and minimize estrogen levels.

Aromatase inhibitors have been used extensively by the medical community as a means to reduce the amount of estrogen that is produced in the body from testosterone. Research studies have reported benefits in men using aromatase inhibitors, demonstrating lower estrogen levels and simultaneously causing an increase in testosterone levels. Therefore, the use of aromatase inhibitors have become common among bodybuilders and other strength athletes who want to maintain highest testosterone levels for maximum anabolic muscle-building effects, while reducing their estrogen levels.

Independent research conducted using aromatase inhibiting substances has reported consistent results for improving testosterone level status among men of all ages. In addition to preserving testosterone levels by blocking the aromatase enzyme conversion to estradiol, increased luteinizing hormone levels are observed. Because LH is responsible for triggering testosterone production, higher LH levels are directly related to promoting higher testosterone levels.

Aromatase inhibitor's effect on testosterone production is likely mediated by the reduction in estradiol production. Reducing estradiol production from testosterone reduces estradiol's negative feedback on the pituitary and hypothalamus glands preventing the shut down of testosterone production. Aromatase inhibitors appear to stimulate pituitary LH secretion sufficiently to cause an increase of endogenous testosterone production.

It is interesting to note that aromatase inhibitors have been given to men of various ages in several studies. In these studies, similar changes in gonadal steroid hormone levels were generally observed. In one noteworthy study of eugonadal elderly men who were given just 2 mg of aromatase inhibitors daily for 9 weeks, researchers reported that blood levels of estradiol decreased by 29% and total testosterone levels increased by an incredible 56%.

7-Arimatase: A New Type of Highly Bio-Active Aromatase Inhibitor

During the MuscleMeds research team's constant effort for creating an improved aromatase-inhibiting product, their attention was drawn to specialized naturally occurring compounds that were determined experimentally to have aromatase-inhibiting properties. As part of their product development protocol, MuscleMeds evaluated the bioavailability of the selected candidate substances. While several of these substances exhibited high aromatase-inhibiting activity, when it came to intestinal absorption and metabolic stability in the body, it was determined that there was a clear grouping of the majority of flavonoids that scored low and only a few that scored high.

When the molecular structures of these aromatase-inhibiting substances was examined closely, an interesting discovery was made. There were key characteristics of the molecular structure that were related to the substances aromatase-inhibiting activity and the bioavailability (intestinal absorption and metabolic stability in the body).

MuscleMeds used this research in their creation of the 7-Arimatase methylated flavone (7-methoxyflavone) molecule. When subjected to independent research, it was determined that 7-Arimatase (also referred to as 7-MF) had one of the highest aromatase-inhibiting scores, with high intestinal absorption and metabolic stability in the body.

This triad of characteristics is extremely important for creating the most effective aromatase inhibitor. You see, even if a substance has high aromatase-inhibiting activity, if it is poorly absorbed or unstable and metabolized quickly in the body, it will be ineffective. Therefore, out of all the substances examined by the MuscleMeds research team, 7-Arimatase was the top choice due to the triad combination of characteristics required for maximum aromatase-inhibiting activity inside the body.

Once the highly effective 7-Arimatase aromatase-inhibitor was created, the MuscleMeds research team focused its attention on determining the ideal route of oral administration. It was determi ned that transmucosal delivery was ideally suited for delivery of 7-Arimatase into the body. A specialized subuccal tablet was created utilizing MuscleMeds exclusive SubZorb technology. This is the fastest route of oral delivery as absorption takes place in the mucosal tissues of the mouth, and any residual that was not absorbed in the mouth is taken up via the digestive system. Getting 7-Arimitase into the bloodstream fast is important to synergistically maximize the testosterone levels produced by Methyl ARIMATEST's Dihydrotase complex, while also reducing estrogen levels.

Breakthrough Dual Action Testosterone Looping and Pooling Effects

Research reveals that because DHT and estrogens are metabolites (breakdown products of testosterone) the body is sensitive to DHT and estrogen levels. When DHT and estrogen levels start to increase, it triggers the body's feedback system to down regulate testosterone levels. So, by keeping DHT and estrogen levels low, this will short-circuit the feedback and keep testosterone production going, which results in optimizing, maintaining and sustaining high T levels like never before possible.

Less conversion of testosterone to estrogen and DHT means that more testosterone is available for anabolic muscle building. Couple this testosterone pooling effect with the signal looping effect to shut down negative feedback inhibition at the pituitary, and you have the most effective testosterone booster ever developed!

Supplement Facts

Formula 1 (Dihydrotase)

Serving Size: 2 Capsules
Servings Per Container: 60

Amount Per Serving % Daily Value

Dihydrotase (Astaxanthin From Haematococcus Pluvialis, Saw Palmetto Berry Lipid Extract From Serenoa Repens) 800mg **

Formula 2 (7-Arimatase)

Serving Size: 1 Tablet
Servings Per Container: 60

Amount Per Serving

7-Arimatase Methylated Flavone (As 7-Methoxyflavone) 25mg *

* Percent Daily Values are based on a 2,000 calorie diet
+ Daily Value not established

Directions:

FORMULA 1 (DIHYDROTASE)
Take two capsules in the morning and two capsules in the evening with water.

FORMULA 2 (7-ARIMATASE)
Place one SubZorb tablet in mouth and let dissolve completely, then swallow. For maximum effects take two Formula 2 SubZorb tablets per day: one tablet in the morning and one tablet in the evening.

Warnings:
For use by healthy adult males only. NOT FOR USE BY INDIVIDUALS UNDER THE AGE OF 18 YEARS. DO NOT USE IF PREGNANT OR NURSING. Consult a physician or licensed qualified healthcare professional before using this product, including, but not limited to, if you have, or have a family history of, prostate cancer, prostate enlargement, heart disease, low "good" cholesterol (HDL), or if you are using any other dietary supplement, prescription drug or over-the-counter drug. Do not exceed recommended serving. Exceeding recommended serving may cause serious adverse health effects. Possible side effects include acne, hair loss, hair growth on the face (in women), aggressiveness and irritability. Discontinue use and call a physician or licensed qualified health care professional immediately if you experience rapid heartbeat, dizziness, blurred vision or other similar symptoms.

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